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Stem Cell (Bone Marrow) Transplantation

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Established in the late 1980's, the Gambino Medical and Science Foundation Bone Marrow Transplantation Unit at Cohen Children’s Medical Center provides state-of-the-art Blood and Marrow Stem Cell therapies to our current patients, and through research improves the results of transplantation for future patients.

Among the diseases for which stem cell transplantation has been curative are: acute and chronic leukemia; myelodysplastic syndrome (MDS); severe aplastic anemia; inherited bone marrow failure syndromes, such as Diamond Blackfan anemia, Shwachman Diamond syndrome, Fanconi anemia; selected patients with sickle cell anemia and thalassemia; immunodeficiency disorders, such as severe combined immunodeficiency and Wiskott-Aldrich syndrome; lysosomal and other metabolic storage diseases; histiocytic disorders and certain solid tumors, including brain tumors, neuroblastoma and Wilms tumor.  Our stem cell transplant physicians have successfully transplanted patients with virtually all of these diseases.

The Stem Cell Transplant Program is fully accredited by the Foundation for Accreditation of Cellular Therapy (FACT) to perform both autologous and allogeneic transplants.  The program remains at the forefront of transplantation research and technology through IRB approved internally initiated studies and research and through affiliations with organizations including the National Marrow Donor Program (NMDP), the Blood and Marrow Transplantation Clinical Trials Network (BMT CTN), the Children’s Oncology Group (COG) and the Pediatric Blood and Marrow Transplant Consortium (PBMTC). 

We are experienced in performing transplants using bone marrow, peripheral blood or umbilical cord blood as the stem cell source.  For patients who lack a compatible family member who could serve as a stem cell donor, we offer transplants from unrelated compatible donors, including umbilical cord blood.  We have become one of the most active pediatric-exclusive stem cell transplantation programs in the country, with outcomes comparable to the best in the world.

In addition, Cohen Children’s Medical Center Stem Cell Transplantation Program has incorporated a transplant survivorship program which provides services to address the unique needs of the survivors in the years following treatment. This program and a follow-up multidisciplinary clinic for stem cell transplant patients are staffed by an endocrinologist, cardiologist, psychologist, neuro-psychologist, nutritionist and a social worker. We also have special programs to facilitate patients' transition to post-transplant life.  These programs address such issues as education, employment, and psychosocial adjustment.
 

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